ConspectusAsymmetric functionalization of inert C-H bonds is undoubtedly a synthetically significant yet challenging bond-forming process, allowing for the preparation of densely functionalized molecules from abundantly available feedstocks. In the past decade, our group and others have found that trivalent phosphorus ligands are capable of facilitating Pd-catalyzed allylic C-H functionalization of α-alkenes upon using p-quinone as an oxidant. In these reactions, a 16-electron Pd(0) complex…
Healthcare Resource Utilization of Ceftolozane/Tazobactam Versus Meropenem for Ventilated Nosocomial Pneumonia from the Randomized, Controlled, Double-Blind ASPECT-NP Trial.
Infect Dis Ther. 2020 Sep 30;:
Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) cause significant inpatient morbidity and mortality. They are especially challenging to diagnose promptly in the intensive care unit because a plethora of other causes can contribute to clinical decline in complex, critically ill patients. The authors describe the diagnosis, management, and prevention of these diseases based on current guidelines and recent evidence.
Management of isoniazid-monoresistant tuberculosis (Hr-TB) in Queensland, Australia: a retrospective case series.
Respir Med. 2020 Sep 21;173:106163
Authors: Wilson M, O’Connor B, Matigian N, Eather G
Vaginal energy-based devices: characterization of adverse events based on the last decade of MAUDE safety reports.
Menopause. 2020 Sep 28;:
Authors: Wallace SL, Sokol ER, Enemchukwu EA
AAV9-mediated AIRE gene delivery clears circulating antibodies and tissue T-cell infiltration in a mouse model of autoimmune polyglandular syndrome type-1.
Clin Transl Immunology. 2020;9(9):e1166
Prophylactic anti-staphylococcal antibiotics for cystic fibrosis.
Cochrane Database Syst Rev. 2020 Sep 30;9:CD001912
Authors: Rosenfeld M, Rayner O, Smyth AR
BACKGROUND: Staphylococcus aure…
Rational antibiotic prescribing in primary care: qualitative study of opportunities and obstacles.
BJGP Open. 2020 Sep 29;:
Authors: Sundvall PD, Skoglund I, Hess-Wargbaner M, Åhrén C
Seasonal Incidence of Respiratory Viral Infections in Telangana, India: Utility of a Multiplex PCR assay to Bridge the Knowledge Gap.
Trop Med Int Health. 2020 Sep 29;:
Authors: Anand M, Pavani N
Epidemiology and risk factors for healthcare-associated infections caused by Pseudomonas aeruginosa.
J Chemother. 2020 Sep 30;:1-8
Authors: Folic MM, Djordjevic Z, Folic N, Radojevic MZ, Jankovic SM