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octubre 30, 2020

Quantification of letermovir in human serum using high-performance liquid chromatography with diode array detection

A simple, rapid, cost-effective and sensitive high-performance liquid chromatography method with diode array detection was developed and validated for the quantification of letermovir, a compound approved for prophylaxis of cytomegalovirus infection and disease in adult recipients of an allogeneic hematopoietic stem cell transplant. Sorafenib was used as internal standard. Samples were pre-treated by liquid-liquid extraction with tert-butyl methylether. Separation was achieved on a XTerra® RP18…

Tuberculosis in Poland in 2018.

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Tuberculosis in Poland in 2018.
Przegl Epidemiol. 2020;74(2):239-257
Authors: Korzeniewska-Koseła M
AIM OF THE STUDY: To evaluate the main features of tuberculosis (TB) epid…