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noviembre 26, 2020

Posaconazole-induced Pseudohyperaldosteronism.

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Posaconazole-induced Pseudohyperaldosteronism.
Kaohsiung J Med Sci. 2020 Nov 24;:
Authors: Tantiprawan J, Sunthornyothin S, Boonchaya-Anant P, Snabboon T
PMID: 33231362 [PubMed – as supplie…

In Vitro Hollow-Fiber Studies Assessing Antibacterial Activity of Ceftolozane/Tazobactam Against Multidrug-Resistant Pseudomonas Aeruginosa

Our hollow-fiber infection model simulated the projected steady-state pharmacokinetics of ceftolozane and tazobactam in lung epithelial lining fluid of patients with pneumonia receiving 3 g of ceftolozane/tazobactam every 8 hours. Results confirmed the previously established in vitro activity of ceftolozane/tazobactam at and above approved breakpoints against multidrug-resistant Pseudomonas aeruginosa, regardless of Pseudomonas-derived cephalosporinase allele.