CONCLUSIONS: Three-quarters of patients with COVID-19 receive antibiotics, prescribing is significantly higher than the estimated prevalence of bacterial co-infection. Unnecessary antibiotic use is likely to be high in patients with COVID-19.
Mangiferin enhances the antifungal activities of caspofungin by destroying polyamine accumulation.
Virulence. 2021 Dec;12(1):217-230
Authors: Shen J, Lu R, Cai Q, Fan L, Yan W, Zhu Z, Yang L, Cao Y
Categorizing susceptibility of clinical isolates of Candida auris to amphotericin B, caspofungin, and fluconazole utilizing the CLSI M44-A2 disk diffusion method.
J Clin Microbiol. 2021 Jan 06;:
CONCLUSIONS: This report highlights the burden of NIs, identifies the major focus for future NI control and prevention programs.
Oral candidiasis prevalence in human immunodeficiency virus-1 and pulmonary tuberculosis coinfection: A systematic review and meta-analysis.
Microb Pathog. 2021 Jan 04;:104720
Authors: Peña DER, Inn…
CONCLUSIONS: NB-BAL is a safe and clinically applicable method for determining the etiology and diagnosis of VAP in the NICU, even in extremely preterm neonates with major chronic comorbidities. Further studies to investigate the diagnostic accuracy and impact of NB-BAL on VAP treatment in neonates are warranted in the future.
Role or oritavancin and dalbavancin in acute bacterial skin and skin structure infections and other potential indications.
Curr Opin Infect Dis. 2021 Jan 05;Publish Ahead of Print:
CONCLUSION: E. coli was the most common causative agent of urinary tract infections in childhood. High resistance to ampicillin, ampicillin-sulbactam, amoxicillin-clavulanate, cefuroxime axetil, and TMP-SMX was detected in all agents in our center.
The purpose of this study is to characterize adverse events (AEs) of clinical interest reported with ceftolozane-tazobactam and ceftazidime-avibactam, as an aid in monitoring patients affected by severe multidrug-resistant Gram-negative infections. We queried the worldwide FDA Adverse Event Reporting System (FAERS) and performed disproportionality analysis, selecting only designated medical events (DMEs) where ceftolozane-tazobactam and ceftazidime-avibactam were reported as suspect. Serious…