Currently browsing

enero 21, 2021

Evaluating the Rapid Emergence of Daptomycin Resistance in <em>Corynebacterium</em>: A Multi-Center Study

Background: Members of the genus Corynebacterium are increasingly recognized as pathobionts and can be very resistant to antimicrobial agents. Previous studies have demonstrated that Corynebacterium striatum can rapidly develop high-level daptomycin resistance (HLDR) (minimum inhibitory concentration [MIC] ≥256 μg/mL). Here we conducted a multi-center study to assay for this in vitro phenotype in diverse Corynebacterium species.Methods: Corynebacterium clinical isolates (n=157) from four medical…