CONCLUSION: SVC boosts the antibiotic effect of ALBCs in the first 24 hours, while maintaining sufficient stability. These findings endorse SVC as a promising additive in septic revision surgery.
CONCLUSION: It was concluded that community pharmacists in Lahore, Pakistan, have good perception regarding AMS and they are practicing it well. But there are few gaps in their practices that must be filled such as dispensing without prescription and dispensing for duration more than prescribed. In addition, there should be strict implantation of guidelines for dispensing antibiotics in order to rationalize antibiotic use and decreasing antibiotic resistance.
CONCLUSION: We report high NPVs for up to 2 weeks between specimen collections, which allows clinicians to use a negative MRSA PCR nasal screen assay to rule out MRSA pneumonia, potentially leading to decreased exposure to MRSA-active antibiotics.
Internet of Things (IoT) in the field of agriculture promises to continuously provide global access to the farming information. The smart agriculture system either gives alert regarding the farm or it recommends for best agriculture field. This paper addresses both irrigation and alert, i.e., Agricultural Irrigation Recommendation and Alert (AIRA) system that operates individually without any correlation. At first, the IoT users of each farm field registers in HDFS, i.e., Hadoop Distributed File…
Mastitis is the most important disease in the dairy industry. Antibiotics are considered to be the first choice in the treatment of the disease. However, the problem of antibiotic residue and antimicrobial resistance, in addition to the impact of antibiotic abuse on public health, leads to many restrictions on uncontrolled antibiotic therapy in the dairy sector worldwide. Researchers have investigated novel therapeutic approaches to replace the use of antibiotics in mastitis control. These…
CONCLUSION: Our research revealed changes in the distribution of microorganisms and antibiotic resistance profile of the pathogens responsible for PJI over time, which could complicate treatment. These findings may serve as a reference for strategies to prevent and empirically treat PJI in China.
In this study we screened twelve newly synthesised N-(substituted phenyl)-2-chloroacetamides for antimicrobial potential relying on quantitative structure-activity relationship (QSAR) analysis based on the available cheminformatics prediction models (Molinspiration, SwissADME, PreADMET, and PkcSM) and verified it through standard antimicrobial testing against Escherichia coli, Staphylococcus aureus, methicillin-resistant S. aureus (MRSA), and Candida albicans. Our compounds met all the screening…
CONCLUSION: Bioreductive activation of DOX and PIRA does not affect their ability to induce apoptosis of sensitive and resistant HL60 leukaemia cells.
The emergence and spread of extensively drug-resistant tuberculosis (XDR-TB) is a serious threat to global health. Therefore, its rapid diagnosis is crucial. The present study aimed to characterize mutations conferring resistance to second line drugs (SLDs) within multidrug Mycobacterium tuberculosis (MDR-MTB) isolates and to estimate the occurrence of XDR-TB in Casablanca, Morocco. A panel of 200 MDR-TB isolates was collected at the Pasteur Institute between 2015-2018. Samples were subjected to…
CONCLUSION: In AML patients, the development of multiple drug resistance (MDR) is the biggest challenge in treating AML patients. Combination therapy with coumarin may be a good choice to overcome the drug resistance in AML patients.
