A case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread.

A case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread.

Med Mycol Case Rep. 2016 Sep;13:22-24

Authors: Snaith J, Burns K, Kok J, Chen S, Cheung NW

Abstract
We document the first case of haematogenous cerebral spread in Rhizopus arrhizus rhino-orbital mucormycosis, and of posaconazole related adrenal insufficiency. A patient presenting with diabetic ketoacidosis and sinusitis was treated with right medial maxillectomy, ethmoidectomy and IV liposomal amphotericin. Orbital exenteration was performed after intraorbital spread of infection. IV caspofungin and posaconazole was added but complicated by adrenal insufficiency. MRI revealed a new left lentiform nucleus and thalamus rim-enhancing lesion indicating haematogenous cerebral spread.

PMID: 27766196 [PubMed - in process]