Analysis of Vancomycin Susceptibility Testing Results for Presumptive Categorization of Telavancin.

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Analysis of Vancomycin Susceptibility Testing Results for Presumptive Categorization of Telavancin.

J Clin Microbiol. 2015 Aug;53(8):2727-30

Authors: Mendes RE, Farrell DJ, Flamm RK, Sader HS, Jones RN

Abstract
Scattergrams between vancomycin and telavancin demonstrated susceptibility agreement rates of 99.96, 99.65, and 100.00% for Staphylococcus aureus, Enterococcus faecalis, and streptococci, respectively. A single very major error was obtained against E. faecalis, while vancomycin-intermediate S. aureus (VISA) and vancomycin-resistant and teicoplanin-susceptible (VanB phenotype) E. faecalis were responsible for major and minor errors. These results support the use of vancomycin to infer telavancin susceptibility among indicated pathogens, except VISA, which should be tested for telavancin susceptibility.

PMID: 26019194 [PubMed - in process]