Antibiotic therapy in children with community-acquired pneumonia

Acta Paediatr. 2021 Jul 15. doi: 10.1111/apa.16030. Online ahead of print.

ABSTRACT

PubMed was reviewed on antibiotic treatment of community-acquired pneumonia (CAP) in children for the years 2011-2020, and three clinical trials in high-income and eight in low-income countries were found. Prospective studies combining laboratory and clinical findings for steering of antibiotic treatment found that five-day courses were equally effective as longer courses. No new antibiotics were launched for children`s CAP during the last ten years. CONCLUSION: Five-day courses are equally effective as 7-10 days courses for CAP in children. Stewardship of antibiotics needs lessening of exposure to antibiotics by better targeting their use and by shortening the lengths of antibiotic courses.

PMID:34265116 | DOI:10.1111/apa.16030