Comparative in Vitro Activities of Ceftaroline and Tedizolid against Clinical Strains of Staphylococcus aureus and Enterococcus: Results from the China Antimicrobial Surveillance Network (CHINET) in 2018.

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Comparative in Vitro Activities of Ceftaroline and Tedizolid against Clinical Strains of Staphylococcus aureus and Enterococcus: Results from the China Antimicrobial Surveillance Network (CHINET) in 2018.

Antimicrob Agents Chemother. 2020 Aug 17;:

Authors: Guo Y, Yang Y, Zheng Y, Wu S, Yin D, Zhu D, Hu F, China Antimicrobial Surveillance Network (CHINET) Study Group

Abstract
The in vitro activities of ceftaroline and tedizolid were compared against clinical isolates of Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium collected from China Antimicrobial Surveillance Network. Ceftaroline demonstrated potent activity against S. aureus (MIC50/90: ≤ 0.25/1 mg/L). Tedizolid was also highly active against S. aureus (MIC50/90: 0.25/0.5 mg/L) and Enterococcus (MIC50/90: 0.5/0.5 mg/L). Our results support the clinical usefulness of ceftaroline and tedizolid in treating gram-positive infections.

PMID: 32816731 [PubMed - as supplied by publisher]