Current spectrum of bacterial infections in patients with nosocomial fever and neutropenia.

Current spectrum of bacterial infections in patients with nosocomial fever and neutropenia.

Caspian J Intern Med. 2013;4(3):698-701

Authors: Yadegarynia D, Fatemi A, Mahdizadeh M, Kabiri Movahhed R, Alizadeh MA

Abstract
Background: Neutropenic patients are vulnerable to a wide spectrum of infectious agents. The aim of this study was to determine the current frequency of bacterial infections in patients with nosocomial fever and neutropenia. Methods: In a retrospective study, the neutropenic patients' specimens with nosocomial fever were cultured on blood and MacConkey agar plates and evaluated at microbiology laboratory. Ninety-five significant isolates as species level were recognized by bacteriological techniques. Results: The most observed microorganism was Escherichia coli, followed by Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae, Coagulase positive staphylococci and Coagulase negative staphylococci. One fungal infection was also observed. Overall, 67% of the organisms were gram negative, 29.8% gram positive, and 3.2% polymicrobial. Conclusion: The changing pattern of infectious agents in neutropenic patients overtime postulates the necessity of other studies to give the most up-to-date insight of the organisms to physicians.

PMID: 24009963 [PubMed]