Detection of carbapenemase producers in Enterobacteriaceae by use of a novel screening medium.

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Detection of carbapenemase producers in Enterobacteriaceae by use of a novel screening medium.

J Clin Microbiol. 2012 Aug;50(8):2761-6

Authors: Nordmann P, Girlich D, Poirel L

Abstract
A Drigalski agar-based culture medium containing an ertapenem, cloxacillin, and zinc sulfate (Supercarba medium) was tested for screening carbapenemase-producing members of the family Enterobacteriaceae. OXA-48 (n = 44), NDM (n = 25), VIM or IMP (n = 27), and KPC producers (n = 18) were detected with a low detection limit. Its overall sensitivity (95.6%) was higher than those of the currently available ChromID ESBL (bioMérieux) and CHROMagar KPC (CHROMagar) screening media. The Supercarba medium provides a significant improvement for detection of the most common types of carbapenemase producers.

PMID: 22357501 [PubMed - indexed for MEDLINE]