Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria.

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Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria.

J Res Med Sci. 2019;24:35

Authors: Barati M, Mirkalantari S, Ansari S, Salari S, Fattahi A

Abstract
Background: The present study was conducted to determine antimicotic susceptibility of Candida species (sp.) from patients with symptomatic candiduria.
Materials and Methods: Identification of Candida sp. and determination of efficacy of most routine antifungals were done using polymerase chain reaction-restriction fragment length polymorphism method and E-test, respectively.
Results: The results from susceptibility test reveal that caspofungin and amphotericin B have high antifungal activity against both albicans (100% and 96%, respectively) and nonalbicans (95.11% and 72.72%, respectively) isolates.
Conclusion: The present study suggests that caspofungin and amphotericin B have the excellent ability to eradicate both Candida groups that showed decreased susceptibility to other compounds.

PMID: 31143236 [PubMed]