Diagnosis and treatment of invasive fungal infections focus on liposomal amphotericin B.

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Diagnosis and treatment of invasive fungal infections focus on liposomal amphotericin B.

Clin Drug Investig. 2013 Feb;33 Suppl 1:S5-14

Authors: Lacerda JF, Oliveira CM

Abstract
Invasive fungal infections (IFIs) are responsible for significant morbidity and mortality, especially in immunocompromised patients and in those requiring admission to an intensive care unit. The epidemiology of IFI is changing, and an increment in non-Aspergillus filamentous fungi and non-Candida albicans species has been observed. The present paper reviews the epidemiology and diagnosis of IFIs. Regarding the treatment of IFIs, it focuses primarily on the role of liposomal amphotericin B in this setting. The main recommendations put forth by expert societies and groups are discussed.

PMID: 23381977 [PubMed - indexed for MEDLINE]