Disseminated fusariosis with cutaneous involvement in hematologic malignancies: report of six cases with high mortality rate.

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Disseminated fusariosis with cutaneous involvement in hematologic malignancies: report of six cases with high mortality rate.

An Bras Dermatol. 2018 Sep-Oct;93(5):726-729

Authors: Hayashida MZ, Seque CA, Enokihara MMSES, Porro AM

Abstract
Fusariosis is due to inhalation or direct contact with conidia. Clinical presentation depends on host's immunity and can be localized, focally invasive or disseminated. Given the severity of this infection and the possibility for the dermatologist to make an early diagnosis, we report six cases of patients with hematologic malignancies, who developed febrile neutropenia an skin lesions suggestive of cutaneous fusariosis. All patients had skin cultures showing growth of Fusarium solani complex, and they received amphotericin B and voriconazole. As this infection can quickly lead to death, dermatologists play a crucial role in diagnosing this disease.

PMID: 30156626 [PubMed - indexed for MEDLINE]