Evaluation of effectiveness of a mouthwash containing antiseptic octenidine dihydrochloride

Stomatologiia (Mosk). 2021;100(2):32-39. doi: 10.17116/stomat202110002132.


THE AIM OF THE STUDY: Was to assess changes in the oral microbiota when using octenidine dihydrochloride mouthwash.

MATERIALS AND METHODS: Quantitative and qualitative changes in the oral microbiota were studied and evaluated after a single rinse, course application and long-term dates.

RESULTS: A single rinse resulted in a significant decrease in the number of pathogenic microorganisms: S. aureus, C. albicans, and Enterobacteriae. After a seven-day course of mouthwash application, the complete disappearance of pathogenic microorganisms: S. aureus, S. albicans, and Enterobacteriae and an increase in the number of Lactobacillus spp were revealed. 7 days after the mouthwash was canceled, there was some recovery of pathogenic (S. aureus, Candida), the number of Lactobacillus spp. remained the same, normal microflora almost completely restored.

CONCLUSION: Octenidine dihydrochloride mouthwash may be recommended for wide use in dental practice in the treatment of various oral pathological conditions, including candidiasis and dysbiosis.

PMID:33874658 | DOI:10.17116/stomat202110002132