Fluconazole underexposure in critically ill patients: a matter of using the right targets?

Antimicrob Agents Chemother. 2021 Mar 29:AAC.00430-21. doi: 10.1128/AAC.00430-21. Online ahead of print.


We read with great interest the paper entitled 'Optimization of fluconazole dosing for the prevention and treatment of invasive candidiasis based on the pharmacokinetics of fluconazole in critically ill patients' recently published by Boonstra JM and colleagues (1).….

PMID:33782011 | DOI:10.1128/AAC.00430-21