- Therapeutic approach to acute otitis media in primary care in an urban area. Delayed antibiotic prescription evaluation
CONCLUSIONS: Delayed prescription in AOM seems to be useful to reduce antibiotics consumption, being necessary to advance in its implantation.
27 February 2021 12:00:00>
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> - A multicentre cluster-randomized clinical trial to improve antibiotic use and reduce length of stay in hospitals: comparison of three measurement and feedback methods
CONCLUSIONS: The decrease in LOS versus baseline likely reflects improvement in the quality of antibiotic use with the stewardship intervention. While the outcomes with the three methods were otherwise similar, stewardship teams preferred data on the quality over the quantity of antibiotic use.
27 February 2021 12:00:00>
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> - Dysphagia after Stroke: An Unmet Antibiotic Stewardship Opportunity
The goal of antibiotic stewardship is to improve antibiotic use, often by reducing unnecessary treatment. Bedside dysphagia screening tools help identify patients at high risk of aspiration following stroke. Presence of dysphagia does not indicate a need for antibiotic treatment. Therefore, this retrospective, cohort study was developed to evaluate the association of dysphagia and antibiotic prescribing following stroke. There were 117 patients included. Patients were placed into 2 cohorts based...
27 February 2021 12:00:00>
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> - Effects of a Comprehensive Antimicrobial Stewardship Program in a Surgical Intensive Care Unit
CONCLUSIONS: A comprehensive ASP treatment decreased the use of APBL and was associated with an improved outcome.
27 February 2021 12:00:00>
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> - The impact of the Auckland cellulitis pathway on length of hospital stay, mortality readmission rate, and antibiotic stewardship
CONCLUSIONS: The implementation of the Auckland cellulitis pathway, readily generalizable to other settings, improved the outcomes in patients with cellulitis, and resulted in an annual saving of approximately 1,000 bed days.
27 February 2021 12:00:00>
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> - Too many pills, too many sick older Australians: Working together is key
BACKGROUND: Australians living in aged care facilities are clinically complex, with multiple comorbidities treated with multiple medicines. Over the past 12 months, there has been unprecedented focus on harm from medications in aged care. This led the Australian Government to fund enhancements to the Residential Medication Management Review (RMMR) program.
26 February 2021 12:00:00>
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> - Impact of Clinical Decision Support on Azithromycin Prescribing in Primary Care Clinics
CONCLUSIONS: Implementation of CDS order panels resulted in a reduction in inappropriate azithromycin prescribing. However, additional improvement in azithromycin prescribing is needed especially for the indications of bronchitis and unspecified URI.
26 February 2021 12:00:00>
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> - Expanding Antimicrobial Stewardship Through Quality Improvement
No abstract
26 February 2021 12:00:00>
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> - Association of a Safety Program for Improving Antibiotic Use With Antibiotic Use and Hospital-Onset Clostridioides difficile Infection Rates Among US Hospitals
CONCLUSIONS AND RELEVANCE: The Agency for Healthcare Research and Quality Safety Program appeared to enable diverse hospitals to establish ASPs and teach frontline clinicians to self-steward their antibiotic use. Safety Program content is publicly available.
26 February 2021 12:00:00>
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> - Rhinovirus-Infected Patients in the COVID-19 Pandemic Period
Human rhinovirus (HRV) is known as one of the most important respiratory pathogens, and the clinical characteristics of HRV infection might be similar to those of coronavirus disease 2019 (COVID-19). We identified 11 HRV-infected patients by polymerase chain reactions of the HRV genes among 151 outpatients with fever. All nine adult patients had underlying diseases and finally improved with the appropriate treatment in this COVID-19 pandemic period. Differential diagnosis between HRV and severe...
26 February 2021 12:00:00>
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> - Prevalence of vancomycin-resistant enterococci in Asia-A systematic review and meta-analysis
WHAT IS KNOWN AND OBJECTIVE: The rise of vancomycin-resistant enterococci (VRE) has been a major health problem in most countries of the world including Asia, since its discovery. There is a paucity of data on VRE in many countries of Asia as well as limited pooled estimates. Therefore, we performed a systematic review and meta-analysis to estimate a pooled prevalence of VRE in Asia.
25 February 2021 12:00:00>
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> - Rural-urban differences in antibiotic prescribing for uncomplicated urinary tract infection
CONCLUSIONS: Inappropriate antibiotic prescribing is quite common for the treatment of uncomplicated UTI. Rural women are more likely to receive inappropriately long antibiotic durations. Antimicrobial stewardship interventions are needed to improve outpatient UTI antibiotic prescribing and to reduce unnecessary exposure to antibiotics, particularly in rural settings.
24 February 2021 12:00:00>
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> - Shorter and longer courses of antibiotics for common infections and the association with reductions of infection-related complications including hospital admissions
CONCLUSION: Equal effectiveness was found between shorter and longer antibiotic courses and the reduction of infection-related hospitalisations. Stewardship programmes should recommend shorter courses of antibiotics for acute infections. Further research is required for treating patients with a complex medical history.
24 February 2021 12:00:00>
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> - Resistors and constipators: Financial impact in an academic medical center, a mathematical model
No abstract
24 February 2021 12:00:00>
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> - The point prevalence and inappropriateness of antibiotic use at hospitals in Turkey: a systematic review and meta-analysis
Inappropriate antimicrobial use is a key problem causing antimicrobial resistance and increased health care costs. Although global point prevalence surveys on antimicrobial prescribing in hospitals were described, there is lack of data from Turkish hospitals. Here, we aimed to perform systematic review and meta-analysis for the point prevalence surveys on antimicrobial prescribing in Turkish hospitals. The Preferred Reporting Items for Systematic reviews and Meta-Analyses guideline was used to...
23 February 2021 12:00:00>
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> - Azole resistance mechanisms in pathogenic <em>M. furfur</em>
Malassezia are emerging fungal pathogens causing opportunistic skin and severe systemic infection. Nosocomial outbreaks are associated with azole resistance and understanding of the underlying mechanisms are limited to knowledge from other fungal species. Herein, we identified distinct antifungal susceptibility patterns in 26 Malassezia furfur isolates derived from healthy and diseased individuals. A Y67F CYP51 mutation was identified in five isolates of M. furfur However, this mutation alone...
23 February 2021 12:00:00>
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> - Dairy veterinarians' perceptions and experts' opinions regarding implementation of antimicrobial stewardship on dairy farms in the western United States
CONCLUSIONS AND CLINICAL RELEVANCE: Additional veterinary oversight of AMU on dairy farms will require engagement by both veterinarians and producers and practical value-added methods for AMS. Continuing education programs should address treatment protocol development, AMU monitoring strategies, and employee training.
23 February 2021 12:00:00>
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> - Clonal diversity and spatial dissemination of multi-antibiotics resistant Staphylococcus aureus pathotypes in Southwest Nigeria
Spread of genetically diverse Staphylococcus aureus characterized with multi-antibiotic resistance and regulated by high level agr functionalities in several communities in southwest Nigeria was investigated and evaluated for infection control. Staphylococcus aureus pathotypes recovered from 256 cases including purulent pus from skin infections, soft tissue aspirates, wounds, otorrhea, eye, throat and endocervical infections were assayed for biofilm and antibiogram. Further genotyped with...
23 February 2021 12:00:00>
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> - Antibiotic use and presumptive pathogens in the Veterans Affairs Healthcare System
CONCLUSIONS: Overall, the vast majority of antibiotic use could be linked to either an infectious diagnosis or microbiological specimen. Nearly half of antibiotic use occurred when there was a specimen collected but no bacterial organism identified, underscoring the need for rapid and improved diagnostics to optimize antibiotic use.
23 February 2021 12:00:00>
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> - Short communication: Comparative performance of 3 on-farm culture systems for detection of mastitis pathogens interpreted by trained and untrained observers
On-farm culture (OFC) systems facilitate pathogen-based mastitis management and can facilitate antimicrobial stewardship on dairy farms. Interpretation of the results, however, may present a challenge for those with limited microbiology experience. Here, we compared results of 3 OFC systems interpreted by trained and untrained observers against results of a standard laboratory reference method (aerobic culture and mass spectrometry). Milk samples (280 quarter and 60 composite) were selected from...
22 February 2021 12:00:00>
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