How to start an antimicrobial stewardship programme in a hospital.
Clin Microbiol Infect. 2019 Aug 21;:
Authors: Mendelson M, Morris AM, Thursky K, Pulcini C
BACKGROUND: Antimicrobial stewardship (AMS) describes a coherent set of actions that ensure optimal use of antimicrobials to improve patient outcomes, while limiting risk of adverse events (including antimicrobial resistance [AMR]). Introduction of AMS programmes in hospitals is part of most national action plans to mitigate AMR, yet the optimal components and actions of such a programme remain undetermined.
OBJECTIVES: To describe how health care professionals can start an antimicrobial stewardship programme in their hospital, the components of such a programme, and the evidence base for its implementation.
SOURCES: National and society-led guidelines on antimicrobial stewardship, peer-reviewed publications, and experience of antimicrobial stewardship experts conducting antimicrobial stewardship programmes.
CONTENT: We provide a step-by-step pragmatic guide to setting up and implementing a hospital antimicrobial stewardship programme in high-income or low- and middle-income countries.
IMPLICATIONS: Antimicrobial stewardship programmes in hospitals are a vital component of national action plans for antimicrobial resistance, and have been shown to significantly reduce AMR, particularly when coupled with infection prevention and control interventions. This step-by-step guide of 'how to' set up an antimicrobial stewardship programme will help health care professionals involved in AMS to optimally design and implement their actions.
PMID: 31445209 [PubMed - as supplied by publisher]