Imipenem and Cilastatin

2021 Jan 18. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006–.


Limited information indicates that imipenem produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush has been reported with beta-lactams, but these effects have not been adequately evaluated. Imipenem-cilastatin and imipenem-cilastatin-relebactam are acceptable in nursing mothers.

PMID:30000046 | Bookshelf:NBK500987