In vitro activities of ravuconazole and isavuconazole against dematiaceous fungi.

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In vitro activities of ravuconazole and isavuconazole against dematiaceous fungi.

Antimicrob Agents Chemother. 2020 Jun 22;:

Authors: Zheng H, Nana S, Mei H, Dong J, Li D, Li X, Liu W

Abstract
The in vitro activities of 11 antifungals against 84 dematiaceous fungi were tested. For most tested fungal species, the MIC values of ravuconazole and isavuconazole were lower than those obtained with itraconazole, voriconazole and posaconazole. Ravuconazole and isavuconazole appear to be more efficient against most dematiaceous fungal infection than other triazoles. However, some pigmented fungi such as B. spicifera and V. botryosa remain more susceptible to other triazoles or to echinocandins.

PMID: 32571811 [PubMed - as supplied by publisher]