In vitro Activity of 8 Antifungal Drugs Against 106 Waterborne and Cutaneous Exophiala Species.

In vitro Activity of 8 Antifungal Drugs Against 106 Waterborne and Cutaneous Exophiala Species.

Antimicrob Agents Chemother. 2013 Oct 7;

Authors: Najafzadeh MJ, Saradeghi Keisari M, Vicente VA, Feng P, Shamsian SA, Rezaei-Matehkolaei A, de Hoog GS, Curfs-Breuker I, Meis JF

Abstract
The in vitro activity of eight antifungal drugs against 106 clinical and environmental isolates of waterborne and cutaneous Exophiala species were tested. The MIC/MEC90s across all strains (n=106) were, in increasing order, as follows: posaconazole 0.063 μg/ml, itraconazole 0.25 μg/ml, micafungin 1 μg/ml, voriconazole 2 μg/ml, isavuconazole 4 μg/ml, caspofungin 8 μg/ml, amphotericin B 16 μg/ml, and fluconazole 64 μg/ml.

PMID: 24100491 [PubMed - as supplied by publisher]