In vitro activity of isavuconazole against Rasamsonia species.

In vitro activity of isavuconazole against Rasamsonia species.

Antimicrob Agents Chemother. 2016 Aug 15;

Authors: Steinmann J, Dittmer S, Houbraken J, Buer J, Rath PM

Abstract
In vitro susceptibilities of a large collection of Rasamsonia isolates (n=47) belonging to seven species were determined for the novel triazole isavuconazole and six other antifungal agents. Isavuconazole and voriconazole had no in vitro activity (minimum inhibitory concentration >32 mg/liter) against isolates from the Rasamsonia argillacea species complex. The echinocandins were the most potent antifungal drugs against all isolates (minimum effective concentration ≤ 0.19 mg/liter).

PMID: 27527087 [PubMed - as supplied by publisher]