In vitro antifungal susceptibility of clinically relevant species belonging to Aspergillus section Flavi.

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In vitro antifungal susceptibility of clinically relevant species belonging to Aspergillus section Flavi.

Antimicrob Agents Chemother. 2013 Jan 18;

Authors: Gonçalves SS, Stchigel AM, Cano J, Guarro J, Colombo AL

Abstract
The in vitro antifungal susceptibility of 77 isolates belonging to different clinically relevant species of Aspergillus section Flavi, including those of different phylogenetic clades of A. flavus, was tested for nine antifungal agents using a microdilution reference method (CLSI, M38-A2). Terbinafine and the echinocandins demonstrated lower MICs/MECs for all species evaluated, followed by posaconazole. Amphotericin B showed MICs ≥ 2 μg/ml for 38 of the 77 isolates (49.4%) tested.

PMID: 23335742 [PubMed - as supplied by publisher]