Incidence and outcome of early Candida peritonitis after liver and pancreas transplantation – Bartoletti – 2012 – Mycoses – Wiley Online Library

Original article
Incidence and outcome of early Candida peritonitis after liver and pancreas transplantation

Michele Bartoletti1,Carlos Cervera1,Irma Hoyo1,Laura Linares1,Gemma Sanclemente1,Jordi Bosch2,3,Francesc Marco2,3,Federico Cofán4,María José Ricart4,Miquel Navasa5,6,Asunción Moreno1
Article first published online: 17 AUG 2012

DOI: 10.1111/j.1439-0507.2012.02227.x

© 2012 Blackwell Verlag GmbH
Keywords:
Candida spp.;peritonitis;antifungal agents

Summary

Candida peritonitis is a potentially life-threatening infection after abdominal transplantation, although there is scant information regarding its incidence and outcome. We analysed the incidence rate and outcome of Candida peritonitis in 717 liver or pancreas transplant recipients. Five cases of Candida peritonitis were diagnosed, representing the second most frequent cause of invasive fungal infection in the cohort. The incidence rate of Candida peritonitis during the first 30 days after transplantation was 6.5 cases/10 000 transplant days in pancreas recipients and 1.2 cases/10 000 transplant days in liver recipients (P = 0.035). Four of the five patients received an echinocandin in combination with other antifungal. All patients were alive and with good graft function at 1-year follow-up. In our series, Candidaperitonitis in liver and pancreas transplant recipients was not uncommon and had a good prognosis.

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