[Infectious complications after kindred kidney allotransplantation].

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[Infectious complications after kindred kidney allotransplantation].

Khirurgiia (Mosk). 2015;(6):44-50

Authors: Volynchik EP, Bogomolova NS, Kuznetsova SM, Bol'shakov LV

It was analyzed the medical records of 231 patients who underwent living kindred donor kidney transplantation. Early postoperative complications were observed in 51 (22%) patients including infectious events in 30 cases namely pyelonephritis (13), pneumonia (6), sepsis (5), wound infection (3), pulmonary tuberculosis (2) and esophageal mycosis (1). Microflora investigation revealed predominantly gram-negative bacteria including enterobacteriaceae (K. pneumoniae, E. coli and E. cloacae) and nonfermentable bacteria (P. aeruginosa, Acinetobacter spp.). Analysis of 7-year antibiotic susceptibility showed that polymyxin, imipenem, cefoperazone/sulbactam and amikacin preserve their activity against enterobacteriaceae and pseudomonas; linezolid, vancomycinum and moxifloxacin - against staphylococcus; voriconazole, amphotericinum B and fluconazole - against Candida spp. These medicines are preferred for antibiotic prevention of perioperative and early postoperative infectious complications.

PMID: 26271423 [PubMed - as supplied by publisher]