Integrating a Rapid Diagnostic Test and Antimicrobial Stewardship: Optimizing Discharge Antibiotics in Skin and Soft Tissue Infections.

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Integrating a Rapid Diagnostic Test and Antimicrobial Stewardship: Optimizing Discharge Antibiotics in Skin and Soft Tissue Infections.

Pediatr Infect Dis J. 2016 Sep 19;

Authors: Yu D, Stach L, Newland JG, Selvarangan R, Goldman J

Abstract
A rapid test to detect methicillin resistance in Staphylococcus aureus through the PBP2a antigen was introduced for pediatric patients hospitalized for purulent skin and soft tissue infections. Integration of this test with physician education and stewardship guidance improved targeted antibiotic use for infections caused by methicillin-susceptible S. aureus (44% to 80%, p<0.001), including when final culture results were not available.

PMID: 27649364 [PubMed - as supplied by publisher]