Linezolid resistance in Staphylococcus haemolyticus – Case series and review of literature.

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Linezolid resistance in Staphylococcus haemolyticus - Case series and review of literature.

Infect Disord Drug Targets. 2019 Aug 07;:

Authors: Gupta V, Gulati N, Sharma S, Gupta R, Soni A, Chander J

Abstract
Coagulase negative Staphylococci are important .The common antibiotics used for the treatment of the infections caused by CoNS are penicillins, oxacillin, ciprofloxacin, clindamycin, erythromycin, gentamicin and vancomycin.Linezolid is an oxazolidinone group of antibiotic with activity against Gram- positive bacteria. It is used for the treatment of serious infections caused by Gram-positive bacteria resistant to other antibiotics, including streptococci, vancomycin-resistant enterococci (VRE). The common antibiotics used for the treatment of the infections caused by CoNS are penicillins, oxacillin, ciprofloxacin, clindamycin, erythromycin, gentamicin and vancomycin. Linezolid is approved as an alternative drug to be given for catheter related blood stream infections. In the earlier studies, linezolid-resistant staphylococci have been reported increasingly all over the world. We are discussing five cases of Linezolid resistant Staphylococcus haemolyticus which were reported in our laboratory during one year from patients with device related infections and also review of literature is being presented for an update. This study emphasizes the judicious use of newer antibiotics to contain the spread of resistance.

PMID: 31389316 [PubMed - as supplied by publisher]