Mixed Infection of Toe Nail Caused by Trichosporon asahii and Rhodotorula mucilaginosa.

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Mixed Infection of Toe Nail Caused by Trichosporon asahii and Rhodotorula mucilaginosa.

Mycopathologia. 2019 Nov 23;:

Authors: Idris NFB, Huang G, Jia Q, Yuan L, Li Y, Tu Z

Abstract
Trichosporon asahii and Rhodotorula mucilaginosa are important fungal species causing disseminated disease in immunocompromised patients. Onychomycosis prevalence rate ranges from 2 to 30%, which were 50% of nail diseases and 30% of superficial mycosis, respectively. Although important, little is known about the co-habitation of T. asahii and R. mucilaginosa in the causation of onychomycosis. Here, we present the co-habitation of T. asahii and R. mucilaginosa as causative agents of onychomycosis in a healthy 41-year-old male in China. Direct microscopic examination, fungal culture and MALDI-TOF MS were employed in isolated pathogens; hence, antifungal susceptibility test was evaluated. T. asahii was sensitive to posaconazole, voriconazole and itraconazole, whereas R. mucilaginosa was sensitive to both 5-flucytosine and amphotericin B. This report highlights the co-habitation of T. asahii and R. mucilaginosa in the causation of onychomycosis and to raise the awareness of this infection among dermatologists.

PMID: 31760556 [PubMed - as supplied by publisher]