New epidemiology of Staphylococcus aureus infections in the Middle East.
Clin Microbiol Infect. 2014 May 26;
Authors: Tokajian S
Staphylococcus aureus is a bacterial pathogen distributed worldwide and is an increasing problem both in hospitals and the community. Global transmission of methicillin-resistant S. aureus (MRSA) has been the subject of many studies. The incidence of colonization with community acquired (CA) MRSA of hospitalized and outpatient was the aim of several studies conducted in the Middle East (Western Asia). The local epidemiology within countries in this region is changing due to the introduction of new strains with the intercontinental exchanges of several clones. ST80-MRSA-IV is one common clone detected in different countries within the region showing country-based differences and hence more likely forming clonal lineages. MRSA is endemic in this region, and is increasing the burden and the difficulty of detecting imported strains. This is also increasing the risk for domestic and global transmission. To counter the threat associated with the high incidence of MRSA carriage and infections, systematic surveillance of both hospital and community isolates is required along with taking appropriate measures designed to limit their spread. Additionally, antibiotic stewardship is needed to contain the further development of the observed resistance and to help in preserving antibiotics as precious therapeutic resources. It is critical for countries in this region to establish national, as well as international initiatives towards better measurements designed to limit and control the spread of infections. Finally more sequence-based studies are needed to better understand the pathogenicity and epidemiology of these important pathogens. This article is protected by copyright. All rights reserved.
PMID: 24861893 [PubMed - as supplied by publisher]