Outpatient Parenteral Antimicrobial Therapy With Ceftolozane/Tazobactam via Continuous Infusion for Multidrug-Resistant Pseudomonas aeruginosa Osteomyelitis

Open Forum Infect Dis. 2020 Sep 15;7(11):ofaa409. doi: 10.1093/ofid/ofaa409. eCollection 2020 Nov.


We present a case of Pseudomonas aeruginosa osteomyelitis treated with surgery and antibiotic therapy with ceftolozane-tazobactam in continuous infusion at home using an elastomeric pump. We discuss the use of ceftolozane-tazobactam in continuous infusion administered at home as an effective alternative for the treatment of multidrug-resistant Pseudomonas aeruginosa osteomyelitis.

PMID:33204747 | PMC:PMC7650892 | DOI:10.1093/ofid/ofaa409