A Multi-Center Study of Posaconazole Therapeutic Drug Monitoring: Exposure-Response and Factors Affecting Concentration

A Multi-Center Study of Posaconazole Therapeutic Drug Monitoring: Exposure-Response and Factors Affecting Concentration Michael J. Dolton1, John E. Ray2, Sharon C-A. Chen3, Kingsley Ng4, Lisa Pont1 and Andrew J. McLachlan1,5,# +Author Affiliations 1Faculty of Pharmacy, University of Sydney, Sydney, Australia 2Clinical Pharmacology & Toxicology, SydPath, St Vincent’s Hospital, Sydney, Australia 3Centre for Infectious Diseases & Microbiology …

Species Identification and Antifungal Susceptibility of Candida Bloodstream Isolates from Population-based Surveillance in Two US Cities: 2008-2011.

J Clin Microbiol. 2012 Aug 8. [Epub ahead of print] Species Identification and Antifungal Susceptibility of Candida Bloodstream Isolates from Population-based Surveillance in Two US Cities: 2008-2011. Lockhart SR, Iqbal N, Ahlquist AM, Farley MM, Harrison LH, Bolden CB, Baughman W, Stein B, Hollick R, Park BJ, Chiller T. Source Mycotic Diseases Branch, Centers for …

Importance of voriconazole therapeutic drug monitoring in pediatric cancer patients with invasive aspergillosis.

Pediatr Blood Cancer. 2012 Aug 8. doi: 10.1002/pbc.24262. [Epub ahead of print] Importance of voriconazole therapeutic drug monitoring in pediatric cancer patients with invasiveaspergillosis. Choi SH, Lee SY, Hwang JY, Lee SH, Yoo KH, Sung KW, Koo HH, Kim YJ. Source Department of Pediatrics, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea. Abstract BACKGROUND: Voriconazole is the drug of …

Are epidemiologic cut-off values predictors of the in vivo efficacy of azoles in experimental aspergillosis?

Diagn Microbiol Infect Dis. 2012 Jul 31. [Epub ahead of print] Are epidemiologic cut-off values predictors of the in vivo efficacy of azoles in experimental aspergillosis? Calvo E, Pastor FJ, Sutton DA, Fothergill AW, Rinaldi MG, Salas V, Guarro J. Source Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, IISPV, Universitat Rovira …

Clinical features of invasive pulmonary aspergillosis vs. colonization in COPD patients distributed by gold stage.

J Infect. 2012 Aug 3. [Epub ahead of print] Clinical features of invasive pulmonary aspergillosis vs. colonization in COPD patients distributed by gold stage. Barberan J, Sanz F, Hernandez JL, Merlos S, Malmierca E, Garcia-Perez FJ, Sanchez-Haya E, Segarra M, Garcia de la Llana F, Granizo JJ, Gimenez MJ, Aguilar L. Source Infectious Diseases Dpt., Hospital Central de la Defensa Gomez Ulla, Gta. del Ejército s/n, 28047 Madrid, Spain. …

Azole-Resistant Invasive Aspergillosis: Relationship to Agriculture

Current Fungal Infection Reports 2012, DOI: 10.1007/s12281-012-0097-7 Clinical Lab Issues (M Pfaller, Section Editor) Azole-Resistant Invasive Aspergillosis: Relationship to Agriculture Christen Rune Stensvold, Lise Nistrup Jørgensen and Maiken Cavling Arendrup Abstract Azole resistance in Aspergillus fumigatus has been increasingly reported particularly over the last decade. Two routes of acquisition are described: selection of resistance during …

Human use of antimicrobial agents. [Rev Sci Tech. 2012] – PubMed – NCBI

Rev Sci Tech. 2012 Apr;31(1):121-33. Human use of antimicrobial agents. Zarb P, Goossens H. Source Vaccine and Infectious Disease Institute, University of Antwerp, Universiteitsplein 1, Wilrijk 2610, Belgium. peter.zarb@gov.mt Abstract Antibiotics have increased life expectancy. Self-medication, even over the Internet, occurs in many countries where antibiotics are classified as prescription-only medicines. Collateral damage caused by …

Drug-specific quality indicators assessing outpatient antibiotic use among French general practitioners.

Eur J Public Health. 2012 Jul 26. [Epub ahead of print] Drug-specific quality indicators assessing outpatient antibiotic use among French general practitioners. Pulcini C, Lions C, Ventelou B, Verger P. Source 1 Centre Hospitalier Universitaire de Nice, Service d’Infectiologie, Nice, France. Abstract Quality indicators assessing the use of antibiotics among general practitioners (GPs) would be …

Posaconazole as successful treatment for fungemia due to Cryptococcus albidus in a liver transplant recipient.

QJM. 2012 Jul 28. [Epub ahead of print] Posaconazole as successful treatment for fungemia due to Cryptococcus albidus in a liver transplant recipient. Cleveland KO, Gelfand MS, Rao V. Source From the Department of Medicine, 1325 Eastmoreland Avenue, Suite 460, Memphis, TN 38104 and Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, …

Indications and outcomes of antifungal therapy in French patients with haematological conditions or recipients of haematopoietic stem cell transplantation. [J Antimicrob Chemother. 2012] – PubMed – NCBI

J Antimicrob Chemother. 2012 Jul 31. [Epub ahead of print] Indications and outcomes of antifungal therapy in French patients with haematological conditions or recipients of haematopoietic stem cell transplantation. Herbrecht R, Caillot D, Cordonnier C, Auvrignon A, Thiébaut A, Brethon B, Michallet M, Mahlaoui N, Bertrand Y, Preziosi P, Ruiz F, Gorin NC, Gangneux JP. …