Potential drug-drug interactions between antiretroviral therapy and treatment regimens for multi-drug resistant tuberculosis: implications for HIV care of MDR-TB co-infected individuals.
Int J Infect Dis. 2019 Apr 13;:
Authors: Mukonzo J, Akillu E, Marconi V, Schinazi RF
HIV-positive TB co-infected patients are at increased risk of multidrug-resistant (MDR)-TB compared to HIV-negative patients. Co-treatment of MDR-TB and HIV is common particularly in Sub-Saharan Africa where the co-morbidity is endemic. We discuss potential cellular metabolic pathway-mediated drug-drug interactions and the possible effect on HIV treatment outcomes of commonly prescribed antiretroviral therapy.
PMID: 30991140 [PubMed - as supplied by publisher]