Principles of Antimicrobial Therapy in Older Adults.

Principles of Antimicrobial Therapy in Older Adults.

Clin Geriatr Med. 2016 Aug;32(3):443-457

Authors: Bradley SF

Abstract
Antibiotic use is common in older adults, and much of it is deemed unnecessary. Complications of antibiotic use may occur as a consequence of changes in age-related physiology and dosing with resulting drug toxicity and secondary infection. Knowing when it is appropriate to initiate antibiotics may help reduce unnecessary antibiotic use and prevent adverse drug events. Careful attention to antibiotic selection, dosing adjustments, and drug-drug interactions may also help prevent antibiotic-related adverse events.

PMID: 27394016 [PubMed - as supplied by publisher]