Regulation of IL-17A-Producing Cells in Skin Inflammatory Disorders

J Invest Dermatol. 2021 Sep 21:S0022-202X(21)01673-0. doi: 10.1016/j.jid.2021.06.036. Online ahead of print.

ABSTRACT

This review focuses on the IL-17A family of cytokines produced by T lymphocytes and other immune cells and how they are involved in cutaneous pathogenic responses. It will also discuss cutaneous dysbiosis and FOXP3+ regulatory T cells in the context of inflammatory conditions linked to IL-17 responses in the skin. Specifically, it will review key literature on chronic mucocutaneous candidiasis and psoriasis.

PMID:34561088 | DOI:10.1016/j.jid.2021.06.036