Research progress of liposome drug delivery system in stomatology

Zhonghua Kou Qiang Yi Xue Za Zhi. 2021 Mar 9;56(3):294-300. doi: 10.3760/cma.j.cn112144-20200627-00372.

ABSTRACT

Liposomes are spherical vesicles with bilayer membrane structure spontaneously formed by phospholipids dispersed in an aqueous medium. Liposomes are excellent drug carrier with amphiphilic properties. Liposomes have good biocompatibility, biodegradability and no immunogenicity. Liposomes can achieve the delivery of the drug, enhance the solubility, improve the stability, reduce the toxic effect of the drug, and improve the therapeutic effect of the loaded drug. In recent years, liposome drug delivery systems have been widely used in dentistry. This article reviews the application of liposome drug delivery systems in caries, dental pulp diseases, periodontitis, implantation, oral anesthesia and oral candidiasis.

PMID:33663162 | DOI:10.3760/cma.j.cn112144-20200627-00372