Resistance Status of Bacteria from a Health Facility in Ghana: A Retrospective Study

J Pathog. 2021 Mar 4;2021:6648247. doi: 10.1155/2021/6648247. eCollection 2021.

ABSTRACT

BACKGROUND: Regardless of the global concerted effort to control the development and spread of antimicrobial resistance, increasing cases are continually documented at many medical centres. This situation is reinforced by inadequate information on the trend of resistance resulting from lack of regular antimicrobial resistance surveillance. The present study sought to detect the number of multidrug-resistant (MDR), extended drug-resistant (XDR), and pandrug-resistant (PDR) bacterial isolates at a health facility in Ghana from January 2018 to July 2020.

METHOD: A total of 800 data on antimicrobial testing results were extracted from the records of the health facility. The extracted data were explored for the detection of MDR, XDR, and PDR. The study further determined the use of antibiotics using the multiple-drug resistance index (MDRI).

RESULTS: Except for Staphylococcus and Neisseria spp., all bacterial isolates showed extremely high (100%) proportion of MDR. Although only Staphylococcus spp. (38 (4.8%)) was observed to be XDR, the rest of the bacteria showed the potential to attain the status of XDR or PDR. MDRI indicated high use of antibiotics in the health facility.

CONCLUSION: The high antimicrobial resistance observed by the study underscores the need for prompt and effective antibiotic resistance control strategies.

PMID:33747569 | PMC:PMC7952191 | DOI:10.1155/2021/6648247