Serum inhibitory and bactericidal activity of telavancin in non-infected subjects with severe renal impairment or end-stage renal disease.

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Serum inhibitory and bactericidal activity of telavancin in non-infected subjects with severe renal impairment or end-stage renal disease.

Diagn Microbiol Infect Dis. 2014 Dec;80(4):327-9

Authors: Barriere SL, Farrell DJ, Rhomberg PR, Jones RN

Abstract
Telavancin biological activity, determined by serum titers against a reference strain of Staphylococcus aureus, was maintained in the serum of subjects with severe renal impairment or end-stage renal disease suggesting that there is no apparent effect of renal function on in vitro activity of telavancin.

PMID: 25306423 [PubMed - indexed for MEDLINE]